Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy.
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DOI: 10.2139/ssrn.4273789
Abstract: Ganoapplins A and B (1 and 2) with a 6/6/6/5/6-fused pentacyclic skeleton containing an aromatic E ring, were obtained from Ganoderma applanatum. Their structures were established through extensive spectroscopic analyses, quantum chemical calculations, including calculated… read more here.
Keywords: inhibit tau; activating autophagy; pentacyclic skeleton; fused pentacyclic ... See more keywords