Tumor-Cell-Surface Adherable Peptide-Drug Conjugate Prodrug Nanoparticles Inhibit Tumor Metastasis and Augment Treatment Efficacy.
Sign Up to like & getrecommendations! Published in 2020 at "Nano letters"
DOI: 10.1021/acs.nanolett.0c00152
Abstract: Cancer metastasis is the main cause of chemotherapeutic failure. Inhibiting the activity of matrix metalloproteinases (MMPs) is a common strategy for reducing metastasis. However, broad-spectrum MMP-inhibitors (MMPI) may cause undesired side effects. Here, we screened… read more here.
Keywords: peptide drug; metastasis; inhibit tumor; drug conjugate ... See more keywords
Zn-doped CuO nanocomposites inhibit tumor growth by NF-κB pathway cross-linked autophagy and apoptosis.
Sign Up to like & getrecommendations! Published in 2019 at "Nanomedicine"
DOI: 10.2217/nnm-2018-0366
Abstract: AIM To investigate the antitumor effects and action mechanism of Zn-doped CuO nanocomposites (Zn-CuONPs). MATERIALS & METHODS Therapeutic effects and mechanisms of Zn-CuONPs were investigated both in vitro and in vivo. RESULTS Zn-CuONPs could inhibit… read more here.
Keywords: cuo nanocomposites; apoptosis; doped cuo; inhibit tumor ... See more keywords
Alternative Strategies to Inhibit Tumor Vascularization
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DOI: 10.3390/ijms20246180
Abstract: Endothelial cells present in tumors show different origin, phenotype, and genotype with respect to the normal counterpart. Various mechanisms of intra-tumor vasculogenesis sustain the complexity of tumor vasculature, which can be further modified by signals… read more here.
Keywords: tumor vascularization; alternative strategies; inhibit tumor; strategies inhibit ... See more keywords