Inhibiting the Aggregation of Aβ by Natural Product Molecules
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400223
Abstract: The abnormal aggregation of Aβ has been considered one of the primary causative factors for Alzheimer's disease. Diverse molecular entities have been developed to mitigate the formation of toxic Aβ aggregates within the brain by… read more here.
Keywords: aggregation natural; natural product; aggregation; inhibiting aggregation ... See more keywords
A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00306
Abstract: Fibrillary aggregates of amyloid-β (Aβ) are the pathological hallmark of Alzheimer's disease (AD). Clearing Aβ deposition or inhibiting Aβ aggregation is a promising approach to treat AD. Experimental studies reported that dopamine (DA), an important… read more here.
Keywords: aggregation; inhibiting aggregation; insight mechanisms; dopamine disrupting ... See more keywords