Synergetic Neuroprotective Effect of Docosahexaenoic Acid and Aspirin in SH-Y5Y by Inhibiting miR-21 and Activating RXRα and PPARα.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and cell biology"
DOI: 10.1089/dna.2017.3643
Abstract: Parkinson's disease (PD) is a serious neurodegenerative disorder that lacks effective therapeutic methods. In this research, expressions of PPARα, RXRα, and miR-21 were evaluated in PD patients and normal controls. To investigate the effects of… read more here.
Keywords: ppar; inhibiting mir; docosahexaenoic acid; rxr ppar ... See more keywords
Inhibiting miR-466b-5p Attenuates Neonatal White Matter Injury by Targeting Lpar1.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlac012
Abstract: miR-466b-5p is aberrantly upregulated in oligodendrocyte precursor cells (OPCs) after white matter injury (WMI). However, its roles in neonatal WMI pathogenesis are unknown. In this study, P3 rats were subjected to hypoxia-ischemia to establish a… read more here.
Keywords: white matter; inhibiting mir; mir 466b; matter injury ... See more keywords
OL-FS13 Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting miR-21- 3p Expression.
Sign Up to like & getrecommendations! Published in 2023 at "Current neuropharmacology"
DOI: 10.2174/1570159x21666230502111013
Abstract: BACKGROUND OL-FS13, a neuroprotective peptide derived from Odorrana livida, can alleviate cerebral ischemia-reperfusion (CI/R) injury, although the specific underlying mechanism remains to be further explored. OBJECTIVE The effect of miR-21-3p on the neural-protective effects of… read more here.
Keywords: cerebral ischemia; inhibiting mir; reperfusion injury; ischemia reperfusion ... See more keywords
Andrographolide Inhibits Angiogenesis by Inhibiting the Mir-21-5p/TIMP3 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.19194
Abstract: Angiogenesis provides nutrients and oxygen to promote tumor growth and affords a channel that facilitates tumor cell entry into the circulation. Andrographolide (Andro) possess anti-tumor activity; however, its direct effect on angiogenesis still needs to… read more here.
Keywords: inhibiting mir; angiogenesis; andrographolide inhibits; angiogenesis inhibiting ... See more keywords