FAF1 blocks ferroptosis by inhibiting peroxidation of polyunsaturated fatty acids.
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DOI: 10.1073/pnas.2107189119
Abstract: SignificanceThe current study reveals the functions of FAF1 in protecting cells from ferroptosis, a novel cell death pathway triggered by PUFA peroxidation. In the absence of FAF1, cultured cells and mice are extremely sensitive to… read more here.
Keywords: peroxidation; faf1; inhibiting peroxidation; ferroptosis inhibiting ... See more keywords