S1PR3 is essential for phosphorylated fingolimod to protect astrocytes against oxygen‐glucose deprivation‐induced neuroinflammation via inhibiting TLR2/4‐NFκB signalling
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DOI: 10.1111/jcmm.13596
Abstract: Fingolimod (FTY720) is used as an immunosuppressant for multiple sclerosis. Numerous studies indicated its neuroprotective effects in stroke. However, the mechanism remains to be elucidated. This study was intended to investigate the mechanisms of phosphorylated… read more here.
Keywords: glucose deprivation; induced neuroinflammation; protect astrocytes; oxygen glucose ... See more keywords