LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "inhibition" as a keyword



Photo from wikipedia

Association of Interleukin 6 Inhibition With Ziltivekimab and the Neutrophil-Lymphocyte Ratio

Sign Up to like & get
recommendations! Published in 2022 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2022.4277

Abstract: This post hoc analysis of the randomized clinical Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition (RESCUE) investigates the association of interleukin 6 ligand inhibition… read more here.

Keywords: inhibition; association interleukin; lymphocyte ratio; ziltivekimab neutrophil ... See more keywords
Photo by rgaleriacom from unsplash

Functional role of glycosphingolipids in contact inhibition of growth in a human mammary epithelial cell line

Sign Up to like & get
recommendations! Published in 2017 at "FEBS Letters"

DOI: 10.1002/1873-3468.12709

Abstract: We have demonstrated previously the involvement of certain glycosphingolipids (GSLs) in ‘contact inhibition’ (dependent on cell‐to‐cell contact) of cell growth. Here, we examined the roles of specific GSLs in contact inhibition of the human epithelial… read more here.

Keywords: epithelial cell; cell line; inhibition; growth ... See more keywords
Photo by runehaugseng from unsplash

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures.

Sign Up to like & get
recommendations! Published in 2022 at "Molecular oncology"

DOI: 10.1002/1878-0261.13221

Abstract: Survival of ovarian carcinoma is associated with the abundance of immunosuppressed CD163high CD206high tumor-associated macrophages (TAMs) and high levels of arachidonic acid (AA) in the tumor microenvironment. Here, we show that both associations are functionally… read more here.

Keywords: raft; lipid raft; microenvironment; acid clinically ... See more keywords
Photo by matmacq from unsplash

Targeted inhibition of STAT3 induces immunogenic cell death of hepatocellular carcinoma cells via glycolysis

Sign Up to like & get
recommendations! Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13263

Abstract: In hepatocellular carcinoma (HCC), the signal transducer and activator of transcription 3 (STAT3) is present in an overactive state that is closely related to tumour development and immune escape. STAT3 inhibition reshapes the tumour immune… read more here.

Keywords: cell death; cell; inhibition; hcc ... See more keywords
Photo from wikipedia

Liraglutide enhances the effect of checkpoint blockade through the inhibition of neutrophil extracellular traps in murine lung and liver cancers.

Sign Up to like & get
recommendations! Published in 2022 at "FEBS open bio"

DOI: 10.1002/2211-5463.13499

Abstract: Glucagon-like peptide-1 (GLP-1) regulates glycemic excursions by augmenting insulin production and inhibiting glucagon secretion. Liraglutide, a long-acting GLP-1 analog, can improve glycemic control for treating type 2 diabetes and prevent neutrophil extravasation in inflammation. Here,… read more here.

Keywords: inhibition; lung liver; liver cancers; murine lung ... See more keywords
Photo from wikipedia

Mechanism of imidazole inhibition of a GH1 β‐glucosidase

Sign Up to like & get
recommendations! Published in 2023 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13595

Abstract: Imidazole is largely employed in recombinant protein purification, including GH1 β‐glucosidases, but its effect on the enzyme activity is rarely taken into consideration. Computational docking suggested that imidazole interacts with residues forming the active site… read more here.

Keywords: active site; mechanism imidazole; inhibition; gh1 glucosidase ... See more keywords
Photo from wikipedia

A Functional Screening Identifies a New Organic Selenium Compound Targeting Cancer Stem Cells: Role of c‐Myc Transcription Activity Inhibition in Liver Cancer

Sign Up to like & get
recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202201166

Abstract: Cancer stem cells (CSCs) are reported to play essential roles in chemoresistance and metastasis. Pathways regulating CSC self‐renewal and proliferation, such as Hedgehog, Notch, Wnt/β‐catenin, TGF‐β, and Myc, may be potential therapeutic targets. Here, a… read more here.

Keywords: inhibition; transcription; cancer stem; functional screening ... See more keywords
Photo from wikipedia

NNMT‐DNMT1 Axis is Essential for Maintaining Cancer Cell Sensitivity to Oxidative Phosphorylation Inhibition

Sign Up to like & get
recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202202642

Abstract: Lacking a clear understanding of the molecular mechanism determining cancer cell sensitivity to oxidative phosphorylation (OXPHOS) inhibition limits the development of OXPHOS‐targeting cancer treatment. Here, cancer cell lines sensitive or resistant to OXPHOS inhibition are… read more here.

Keywords: inhibition; sensitivity; oxphos inhibition; cancer cell ... See more keywords
Photo by toddcravens from unsplash

Toward complement inhibition 2.0: Next generation anticomplement agents for paroxysmal nocturnal hemoglobinuria

Sign Up to like & get
recommendations! Published in 2018 at "American Journal of Hematology"

DOI: 10.1002/ajh.25016

Abstract: Therapeutic complement inhibition by eculizumab has revolutionized the treatment of paroxysmal nocturnal hemoglobinuria (PNH) with a major impact on its natural history. Nevertheless, emerging unmet clinical needs may benefit from the development of novel complement… read more here.

Keywords: paroxysmal nocturnal; inhibition; nocturnal hemoglobinuria; complement inhibition ... See more keywords
Photo by eiskonen from unsplash

Synthesis, characterization, corrosion inhibition of mild steel in HCl (0.5 N) solution and solid‐state electrical conductivity of new Co(II), Ni(II), Cu(II) and Zn(II) complexes

Sign Up to like & get
recommendations! Published in 2017 at "Applied Organometallic Chemistry"

DOI: 10.1002/aoc.3572

Abstract: This work consists of a study of the corrosion-inhibiting and semiconducting properties of new binuclear Co(II), Ni(II), Cu(II) and Zn(II) complexes with a Schiff base, H2L, obtained from the 2:1 M condensation of salicylaldehyde and… read more here.

Keywords: corrosion inhibition; characterization corrosion; inhibition; corrosion ... See more keywords
Photo by anritikhon from unsplash

Inhibition of histone acetylation and deacetylation enzymes affects longevity, development, and fecundity in the pea aphid (Acyrthosiphon pisum).

Sign Up to like & get
recommendations! Published in 2019 at "Archives of insect biochemistry and physiology"

DOI: 10.1002/arch.21614

Abstract: Histone acetylation is an evolutionarily conserved epigenetic mechanism of eukaryotic gene regulation which is tightly controlled by the opposing activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). In insects, life-history traits such as longevity… read more here.

Keywords: histone acetylation; inhibition; aphid acyrthosiphon; acyrthosiphon pisum ... See more keywords