Targeting Apoptosis Inhibition to Activate Antitumor Immunity.
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DOI: 10.1016/j.it.2019.11.002
Abstract: A recent study by Rodriguez-Ruiz et al. suggests that inhibition of apoptotic caspases can augment radiation-induced antitumor immunity, independent of type I IFN. Their findings also highlight caspase-independent cytotoxicity in radiation therapy-induced antitumor immunity, proposing SLC7A2 as… read more here.
Keywords: immunity; antitumor immunity; targeting apoptosis; activate antitumor ... See more keywords