Inhibition of NF-κB activation improves insulin resistance of L6 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine journal"
DOI: 10.1507/endocrj.ej17-0012
Abstract: To explore the role of NF-κB activation in the development of insulin resistance and investigate whether or not that the inhibition of NF-κB activation by PDTC will improve the insulin resistance of L6 cells exposed… read more here.
Keywords: resistance cells; inhibition activation; activation; insulin resistance ... See more keywords
The protein kinase CK1: Inhibition, activation, and possible allosteric modulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.916232
Abstract: Protein kinases play a vital role in biology and deregulation of kinases is implicated in numerous diseases ranging from cancer to neurodegenerative diseases, making them a major target class for the pharmaceutical industry. However, the… read more here.
Keywords: protein kinase; ck1 inhibition; kinase ck1; possible allosteric ... See more keywords
Recent Trends in Enzyme Inhibition and Activation in Drug Design
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DOI: 10.3390/molecules26010017
Abstract: It is known that enzymes are involved in many pathological conditions, such as inflammation, diabetes, microbial infections, HIV, neoplastic, neglected diseases and others [...]. read more here.
Keywords: enzyme inhibition; trends enzyme; drug design; recent trends ... See more keywords