Docking Approach to Predict Inhibition Activity of New Pt(II) Complexes Against Kinase Protein and Human DNA: Full Characterization, HF-FC Modeling and Genotoxicity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inorganic and Organometallic Polymers and Materials"
DOI: 10.1007/s10904-019-01233-w
Abstract: New series of Pt(II)–azaindazole complexes, were synthesized and also characterized by, analytical, spectral and computational tools. All synthesized Pt(II)-complexes, appeared as mononuclear with bi-dentate mode of bonding. Octahedral arrangement as well as square-planer, were proposed… read more here.
Keywords: kinase protein; docking approach; dna; inhibition ... See more keywords
Inhibition of NF-κB activity by aminoguanidine alleviates neuroinflammation induced by hyperglycemia
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-017-0013-5
Abstract: Neuroinflammation is a key feature of cerebral complication which is associated with diabetes mellitus (DM). Inducible nitric oxide synthase (iNOS) is implicated in the pathogenesis of neuroinflammation. However, how iNOS facilitates the development of inflammation… read more here.
Keywords: inhibition activity; diabetic mice; brain; neuroinflammation ... See more keywords
Enterocin Structural Gene Screening in Enterococci from Pannon White Breed Rabbits
Sign Up to like & getrecommendations! Published in 2020 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-020-09641-y
Abstract: This study was focused on screening the most frequently occurring enterocin (Ents) genes in faecal enterococci from the Pannon White breed of rabbits, in which this parameter never has been tested. Enterococci tested were Ent… read more here.
Keywords: enterococci pannon; breed rabbits; white breed; inhibition activity ... See more keywords
Chemical constituents from Parrotia persica- Structural derivatization and their potential prolyl endopeptidase inhibition activity.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103526
Abstract: The current study was aimed to evaluate the prolyl endopeptidase (PEP) inhibitory activity of glutinol (1), azadiradione (2), quercetin 3-O-β-d-glactopyranoside (3), catechin (4), quercetin (5), naringenin (6) isolated from Parrotia persica C. A. Mey. Naringenin… read more here.
Keywords: prolyl endopeptidase; inhibition; parrotia persica; inhibition activity ... See more keywords
Evaluation of algal photosynthesis inhibition activity for dissolved organic matter with the consideration of inorganic and coloring constituents.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.02.106
Abstract: The effect of waterborne ingredient on ecosystem has been of great interest. In the present study, the evaluation method using algal photosynthesis inhibition assay with dual-channel pulse amplitude modulation (PAM) system was established for a… read more here.
Keywords: photosynthesis inhibition; algal photosynthesis; inhibition; inhibition activity ... See more keywords
Lectin-based assay for the determination of the inhibition activity of small molecule inhibitors of neuraminidases.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2020.11.016
Abstract: Small molecules inhibitors of neuraminidases (NAs) are ones of the most prospective molecules proposed for the treatment of influenza viruses. The determination of their inhibition activity in vitro is an important step during the development… read more here.
Keywords: determination inhibition; inhibitors neuraminidases; inhibition; inhibition activity ... See more keywords
Synthesis, crystal structure and Hirschfeld surface analyses of an alkyl amine based salt, [C5H16N2][ZnCl4] and its enzyme inhibition activity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Saudi Chemical Society"
DOI: 10.1016/j.jscs.2016.12.002
Abstract: Abstract A novel ionic zinc salt based on alkyl amine is reported. The structure of the studied salt is established by crystal X-ray crystallography, FT-IR and NMR spectroscopy. Furthermore, Hirschfeld surface analyses of the studied… read more here.
Keywords: surface analyses; inhibition activity; enzyme inhibition; salt ... See more keywords
Design, Bioactivity, and Action Mechanism of Pyridinecarbaldehyde Phenylhydrazone Derivatives with Broad-Spectrum Antifungal Activity.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c04078
Abstract: Replacing old pesticides with new pesticide varieties has been the main means to solve pesticide resistance. Therefore, it is necessary to research and develop new antifungal agents for plant protection. In this study, a series… read more here.
Keywords: pyridinecarbaldehyde phenylhydrazone; broad spectrum; phenylhydrazone derivatives; inhibition activity ... See more keywords
Design, Synthesis and Bioactivity of Benzyl Propiolates with Broad-Spectrum Inhibition Activity on Phytopathogenic Fungi.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c06770
Abstract: As part of our continuing research on propiolic acid derivatives, a series of benzyl propiolate derivatives and analogues were designed, synthesized, and investigated for inhibition activity in vitro and in vivo on phytopathogenic fungi, structure-activity… read more here.
Keywords: broad spectrum; fungi; phytopathogenic fungi; inhibition activity ... See more keywords
Antimicrobial and Biofilm Inhibition Activity of Novel Biobased Quaternary Ammonium Salts
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c06267
Abstract: The growing threat of antibiotic-resistant bacteria continues to be one of the biggest challenges facing public health. As a result, there is an increasing focus on developing new substances with both antimicrobial and biofilm inhibition… read more here.
Keywords: antimicrobial biofilm; inhibition; inhibition activity; biofilm inhibition ... See more keywords
Real-time monitoring and inhibition of the activity of carbapenemase in live bacterial cells: application to screening of β-lactamase inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/d0nj03475d
Abstract: Antibiotic resistance mediated by β-lactamases including metallo-β-lactamases (MβLs) has become an emerging threat. read more here.
Keywords: carbapenemase live; time monitoring; real time; monitoring inhibition ... See more keywords