Inhibition of ADAM10 ameliorates doxorubicin-induced cardiac remodeling by suppressing N-cadherin cleavage
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DOI: 10.1515/biol-2021-0081
Abstract: Abstract The present research was designed to examine the effects of disintegrin metalloproteinases 10 (ADAM10) on the doxorubicin (DOX)-induced dilated cardiomyopathy (DCM) and the mechanisms involved, with a focus on ADAM10-dependent cleavage of N-cadherin. The… read more here.
Keywords: adam10; cleavage; cardiac remodeling; cadherin cleavage ... See more keywords