Controlled Inhibition of Apoptosis by Photoactivatable Caspase Inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2020.08.001
Abstract: Caspases control regulated cell death (apoptosis), a process that is crucial in the development of multicellular organisms as well as in various diseases. In order to spatiotemporally study apoptosis, we here develop photoactivatable caspase inhibitors.… read more here.
Keywords: photoactivatable caspase; apoptosis; controlled inhibition; caspase inhibitors ... See more keywords
Baicalein protects PC12 cells from Aβ25-35-induced cytotoxicity via inhibition of apoptosis and metabolic disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117471
Abstract: AIMS This study aimed to explore the protective effects and possible mechanisms of baicalein on Aβ25-35-induced toxicity. MAIN METHODS Thioflavin-T (Th-T) dye was used to determine the effects of baicalein on Aβ25-35 aggregation in vitro.… read more here.
Keywords: pc12 cells; apoptosis; metabolic disorders; apoptosis metabolic ... See more keywords
Effects of Antibacterial Co‐Cr‐Mo‐Cu Alloys on Osteoblast Proliferation, Differentiation, and the Inhibition of Apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Orthopaedic Surgery"
DOI: 10.1111/os.13253
Abstract: To investigate the effects of antibacterial Co‐Cr‐Mo‐Cu alloys with different Cu contents on osteoblast proliferation, differentiation, and the inhibition of apoptosis to optimize the selection of surgical implantation. read more here.
Keywords: osteoblast proliferation; antibacterial alloys; effects antibacterial; inhibition apoptosis ... See more keywords
The Role of Inhibition of Apoptosis in Acute Leukemias and Myelodysplastic Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00192
Abstract: Avoidance of apoptosis is a key mechanism that malignancies, including acute leukemias and MDS, utilize in order to proliferate and resist chemotherapy. Recently, venetoclax, an inhibitor of the anti-apoptotic protein BCL-2, has been approved for… read more here.
Keywords: apoptosis acute; acute leukemias; role inhibition; myelodysplastic syndrome ... See more keywords
NIPAAm-MMA nanoparticle-encapsulated visnagin ameliorates myocardial ischemia/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2018.7922
Abstract: The main method for the treatment of acute myocardial infarction (AMI) is percutaneous coronary intervention; however percutaneous coronary intervention will induce ischemia/reperfusion (IR) injury, resulting in the loss of cardiac function and cardiomyocyte death. An… read more here.
Keywords: autophagy inhibition; visnagin; ischemia reperfusion; reperfusion injury ... See more keywords