Inhibition of ASIC1a-Mediated ERS Improves the Activation of HSCs and Copper Transport Under Copper Load
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DOI: 10.3389/fphar.2021.653272
Abstract: Hepatolenticular degeneration (HLD) is an autosomal recessive genetic disease caused by the toxic accumulation of copper in the liver. Excessive copper will disrupt the redox balance in cells and tissues, causing ischemia, hypoxia, and inflammation.… read more here.
Keywords: inhibition asic1a; copper; expression; copper accumulation ... See more keywords