Inhibition of the V-ATPase by Archazolid A: A New Strategy to Inhibit EMT
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-17-0129
Abstract: Epithelial–mesenchymal transition (EMT) induces tumor-initiating cells (TIC), which account for tumor recurrence, metastasis, and therapeutic resistance. Strategies to interfere with EMT are rare but urgently needed to improve cancer therapy. By using the myxobacterial natural… read more here.
Keywords: inhibition atpase; emt; atpase; atpase archazolid ... See more keywords
Inhibition of Na+, K+ -ATPase with ouabain is detrimental to equine blastocysts
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DOI: 10.21451/1984-3143-ar2019-0079
Abstract: Abstract Although equine blastocysts ≤ 300 µm in diameter can be successfully vitrified, larger equine blastocysts are not good candidates for cryopreservation. As Na+, K+-ATPase is involved in maintaining blastocyst expansion, perhaps inhibition of this… read more here.
Keywords: inhibition atpase; ouabain; equine blastocysts;
Novel Isoxazole Derivative Attenuates Ethanol-Induced Gastric Mucosal Injury through Inhibition of H+/K+-ATPase Pump, Oxidative Stress and Inflammatory Pathways
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DOI: 10.3390/molecules27165065
Abstract: Isoxazole derivatives are significant enough due to their wide range of pharmacological and therapeutic activities. The purpose of the current study is to use computational, in vitro, in vivo, and extensive molecular approaches to examine… read more here.
Keywords: inhibition atpase; ethanol induced; inflammatory pathways; atpase ... See more keywords