Inhibition of AURKA kinase activity suppresses collective invasion in a microfluidic cell culture platform
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DOI: 10.1038/s41598-017-02623-1
Abstract: Tumor local invasion is the first step of metastasis cascade which remains the key obstacle for cancer therapy. Collective cell migration plays a critical role in tumor invading into surrounding tissues. In vitro assays fail… read more here.
Keywords: invasion; microfluidic cell; inhibition aurka; collective invasion ... See more keywords