Inhibition of autophagy reduces the rate of fluoride‐induced LS8 apoptosis via regulating ATG5 and ATG7
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23280
Abstract: Excessive fluoride affects ameloblast differentiation and tooth development. The fate of fluorinated ameloblasts is determined by multiple signaling pathways in response to a range of stimuli. Both autophagy and apoptosis are involved in the regulation… read more here.
Keywords: inhibition autophagy; atg5 atg7; fluoride induced; apoptosis ... See more keywords
Inhibition of autophagy reverses alcohol-induced hepatic stellate cells activation through activation of Nrf2-Keap1-ARE signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Biochimie"
DOI: 10.1016/j.biochi.2017.12.013
Abstract: BACKGROUND Numerous documents have indicated a critical role of autophagy in alcoholic liver fibrosis (ALF), but few papers have reported its function in hepatic stellate cells (HSCs) activation. The current study aimed to investigate the… read more here.
Keywords: inhibition autophagy; nrf2 keap1; autophagy; activation ... See more keywords
Inhibition of autophagy impairs acrosome and mitochondrial crista formation during spermiogenesis in turtle: Ultrastructural evidence.
Sign Up to like & getrecommendations! Published in 2019 at "Micron"
DOI: 10.1016/j.micron.2019.03.006
Abstract: Autophagy is a subcellular process that is extensively involved in spermiogenesis. In this study, we observed ultrastructural malformation of acrosome and mitochondrial cristae during the spermiogenesis of Chinese soft-shelled turtle due to the inhibition of… read more here.
Keywords: spermiogenesis; cristae; inhibition autophagy; formation ... See more keywords
Inhibition of Autophagy Promoted Apoptosis and Suppressed Growth of Hepatocellular Carcinoma Upon Photothermal Exposure.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2019.2714
Abstract: Photothermal therapy (PTT) is a recently developed and promising strategy for the treatment of hepatocellular carcinoma (HCC). However, apoptosis has been extensively investigated as the mechanism of the underlying effect of PTT on cancer to… read more here.
Keywords: apoptosis; inhibition autophagy; hepatocellular carcinoma; ptt ... See more keywords
Potential of Bacillus subtilis lipopeptides in anti-cancer I: induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells
Sign Up to like & getrecommendations! Published in 2018 at "AMB Express"
DOI: 10.1186/s13568-018-0606-3
Abstract: The lipopeptide iturin from Bacillus subtilis has been found to have a potential inhibitory effect on breast cancer, alveolar adenocarcinoma, renal carcinoma, and colon adenocarcinoma. In this study, the potential of B. subtilis lipopeptides (a… read more here.
Keywords: apoptosis; inhibition autophagy; k562; paraptosis ... See more keywords
Duloxetine Enhances TRAIL-mediated Apoptosis via AMPK-mediated Inhibition of Autophagy Flux in Lung Cancer Cells
Sign Up to like & getrecommendations! Published in 2019 at "AntiCancer Research"
DOI: 10.21873/anticanres.13877
Abstract: Background/Aim: The antidepressant duloxetine is known as a serotonin–norepinephrine reuptake inhibitor, used for treating depression and anxiety. TRAIL selectively induces cell death in a variety of tumor cells by binding to its membrane death receptor… read more here.
Keywords: trail mediated; apoptosis; inhibition autophagy; duloxetine ... See more keywords
Inhibition of Autophagy Increases Cell Death in HeLa Cells through Usnic Acid Isolated from Lichens
Sign Up to like & getrecommendations! Published in 2023 at "Plants"
DOI: 10.3390/plants12030519
Abstract: The Western Ghats, India, is a hotspot for lichen diversity. However, the pharmacological importance of lichen-associated metabolites remains untapped. This study aimed to evaluate the cytotoxic potential of lichens of this region. For this, sixteen… read more here.
Keywords: inhibition autophagy; usnic acid; cytotoxicity; hela cells ... See more keywords
Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gynecologic Oncology"
DOI: 10.3802/jgo.2017.28.e33
Abstract: Objective Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor prognosis due to chemoresistance. The association of autophagy-related proteins and clinical implementation in CCC has not been determined. Methods The present study… read more here.
Keywords: protein; autophagy protein; inhibition autophagy; expression ... See more keywords
Inhibition of autophagy enhances cinobufagin‑induced apoptosis in gastric cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology reports"
DOI: 10.3892/or.2018.6837
Abstract: Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans. Cinobufagin is one of the active ingredients in the anticancer Chinese medicine called Chan Su, which was demonstrated to be an effective treatment… read more here.
Keywords: apoptosis; gastric cancer; inhibition autophagy; cinobufagin ... See more keywords