Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury
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DOI: 10.1126/sciadv.abq2611
Abstract: DNA double-strand breaks occur in many acute and long-term neurological conditions, including neurodegeneration, neurotrauma, and stroke. Nonrepaired breaks chronically activate the DNA damage response in neurons, leading to neural dysfunction and apoptosis. Here, we show… read more here.
Keywords: chk2; inhibition chk2; chk2 promotes; functional recovery ... See more keywords