Sodium-Glucose Co-transporters and Their Inhibition: Clinical Physiology.
Sign Up to like & getrecommendations! Published in 2017 at "Cell metabolism"
DOI: 10.1016/j.cmet.2017.04.011
Abstract: Sodium-glucose cotransporter-2 (SGLT2) is selectively expressed in the human kidney, where it executes reabsorption of filtered glucose with a high capacity; it may be overactive in patients with diabetes, especially in the early, hyperfiltering stage… read more here.
Keywords: sodium glucose; inhibition clinical; transporters inhibition; glucose transporters ... See more keywords
mTOR Inhibition and Clinical Transplantation: Kidney.
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DOI: 10.1097/tp.0000000000001692
Abstract: T mammalian target of rapamycin (mTOR) inhibitor class of immunosuppressive drugs were introduced more than 15 years ago as a new opportunity to create selective antirejection therapy in solid organ transplantation. In particular, absence of… read more here.
Keywords: clinical transplantation; inhibition clinical; mtor inhibition; transplantation ... See more keywords
mTOR Inhibition and Clinical Transplantation: Heart.
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DOI: 10.1097/tp.0000000000001921
Abstract: This brief overview discusses recent data on the use of mammalian target of rapamycin (mTOR) inhibitors in heart transplantation. Trials on de novo use have shown good efficacy of mTOR inhibitors; however, adverse events are… read more here.
Keywords: heart; clinical transplantation; inhibition clinical; mtor inhibition ... See more keywords