Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103897
Abstract: Some metabolic enzyme inhibitors can be used in the treatment of many diseases. Therefore, synthesis and determination of alternative inhibitors are essential. In this study, the inhibition effect of newly synthesized compounds on carbonic anhydrase… read more here.
Keywords: carbonic anhydrase; inhibition effects; inhibition; molecular docking ... See more keywords
Synergistic inhibition effects of hydrophilic monomeric substances on CH4 hydrate as revealed by experimental and computational approaches
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.130794
Abstract: Abstract In this study, urea (U), acetamide (A), and glycine (G), which are easily decomposable, were suggested as kinetic hydrate inhibitors (KHIs) and potential synergists for CH4 hydrate. The inhibition performance of these substances was… read more here.
Keywords: monomeric substances; synergistic inhibition; ch4 hydrate; inhibition effects ... See more keywords
In situ scanning tunneling microscopy study of 2-mercaptobenzimidazole local inhibition effects on copper corrosion at grain boundary surface terminations
Sign Up to like & getrecommendations! Published in 2021 at "Electrochimica Acta"
DOI: 10.1016/j.electacta.2021.138150
Abstract: Abstract New insight on local inhibition effects of 2-mercaptobenzimidazole (MBI) on early stage intergranular corrosion of copper in hydrochloric acid solution is reported from in situ analysis at the nanometer scale and comparison with 2-mercaptobenzothiazole… read more here.
Keywords: microscopy; surface; corrosion; local inhibition ... See more keywords
Evaluation of the inhibition effects of apatinib on human and rat cytochrome P450.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.08.010
Abstract: Apatinib, a small molecule anti-angiogenic drug, is proven to be safe and effective for treatment of advanced gastric cancer (AGC). It is also a single drug that significantly prolongs survival after failure of standard chemotherapy… read more here.
Keywords: apatinib human; inhibition effects; inhibition; effects apatinib ... See more keywords
Getting rid of ‘rain’ and ‘stars’: Mitigating inhibition effects on ddPCR data analysis, the case study of the invasive crayfish Pacifastacus leniusculus in the streams of Luxembourg
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0275363
Abstract: ddPCR is becoming one of the most widely used tool in the field of eDNA-based aquatic monitoring. Although emulsion PCR used in ddPCR confers a partial mitigation to inhibition due to the high number of… read more here.
Keywords: inhibition; ddpcr data; inhibition effects; concentration ... See more keywords
Modelling Methane Hydrate Saturation in Pores: Capillary Inhibition Effects
Sign Up to like & getrecommendations! Published in 2021 at "Energies"
DOI: 10.3390/en14185627
Abstract: Experimental and field observations evidence the effects of capillarity in narrow pores on inhibiting the thermodynamic stability of gas hydrates and controlling their saturation. Thus, precise estimates of the gas hydrate global inventory require models… read more here.
Keywords: inhibition effects; hydrate; saturation; capillary inhibition ... See more keywords
Assessment of Demineralization Inhibition Effects of Dentin Desensitizers Using Swept-Source Optical Coherence Tomography
Sign Up to like & getrecommendations! Published in 2021 at "Materials"
DOI: 10.3390/ma14081876
Abstract: The purpose of this study was to evaluate the mechanism of action and the inhibiting effects of two types of desensitizers against dentin demineralization using pre-demineralized hypersensitivity tooth model in vitro. In this study, we… read more here.
Keywords: days demineralization; inhibition effects; demineralization; three days ... See more keywords
Screening of Carbonic Anhydrase, Acetylcholinesterase, Butyrylcholinesterase, and α-Glycosidase Enzyme Inhibition Effects and Antioxidant Activity of Coumestrol
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27103091
Abstract: Coumestrol (3,9-dihydroxy-6-benzofuran [3,2-c] chromenone) as a phytoestrogen and polyphenolic compound is a member of the Coumestans family and is quite common in plants. In this study, antiglaucoma, antidiabetic, anticholinergic, and antioxidant effects of Coumestrol were… read more here.
Keywords: carbonic anhydrase; antioxidant activity; activity coumestrol; inhibition effects ... See more keywords
Synthesis of Novel Bromophenol with Diaryl Methanes—Determination of Their Inhibition Effects on Carbonic Anhydrase and Acetylcholinesterase
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27217426
Abstract: In this work, nine new bromophenol derivatives were designed and synthesized. The alkylation reactions of (2-bromo-4,5-dimethoxyphenyl)methanol (7) with substituted benzenes 8–12 produced new diaryl methanes 13–17. Targeted bromophenol derivatives 18–21 were synthesized via the O-Me… read more here.
Keywords: bromophenol; diaryl methanes; carbonic anhydrase; inhibition effects ... See more keywords
Green Synthesis, Characterization, Antioxidant, Antibacterial and Enzyme Inhibition Effects of Chestnut (Castanea sativa) Honey-Mediated Silver Nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062762
Abstract: In this study, chestnut honey-based silver nanoparticles (CH-AgNPs) were synthesized at different temperatures (30, 60 and 90 °C) and these nanoparticles were characterized by different techniques such as UV–vis spectrophotometer, Fourier transform infrared spectroscopy (FTIR),… read more here.
Keywords: inhibition; honey; inhibition effects; green synthesis ... See more keywords