Inhibition of fatty acid amide hydrolase in the CNS prevents and reverses morphine tolerance in male and female mice
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DOI: 10.1111/bph.15031
Abstract: Fatty acid amide hydrolase (FAAH) is an intracellular serine amidase that terminates the signalling of various lipid messengers involved in pain regulation, including anandamide and palmitoylethanolamide. Here, we investigated the effects of pharmacological or genetic… read more here.
Keywords: acid amide; tolerance; fatty acid; amide hydrolase ... See more keywords
Inhibition of Fatty Acid Oxidation as a New Target To Treat Primary Amoebic Meningoencephalitis
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00344-20
Abstract: Primary amoebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living amoeba Naegleria fowleri. The amoeba migrates along the olfactory nerve to the brain, resulting in seizures, coma, and, eventually, death. Previous research… read more here.
Keywords: oxidation; inhibition fatty; amoebic meningoencephalitis; primary amoebic ... See more keywords