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Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-01366-3

Abstract: Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported recently that stress targets visceral adipose tissue (VAT), inducing lipolysis, low-grade inflammation with production of… read more here.

Keywords: xanthine oxidase; inhibition febuxostat; stress induced; stress ... See more keywords