Inhibition of fungal pathogenicity by targeting the H2S-synthesizing enzyme cystathionine β-synthase
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.add5366
Abstract: The global emergence of antifungal resistance threatens the limited arsenal of available treatments and emphasizes the urgent need for alternative antifungal agents. Targeting fungal pathogenic functions is an appealing alternative therapeutic strategy. Here, we show… read more here.
Keywords: cystathionine synthase; inhibition fungal; synthase; fungal pathogenicity ... See more keywords
A Highlight on the Inhibition of Fungal Carbonic Anhydrases as Drug Targets for the Antifungal Armamentarium
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22094324
Abstract: Carbon dioxide (CO2), a vital molecule of the carbon cycle, is a critical component in living organisms’ metabolism, performing functions that lead to the building of compounds fundamental for the life cycle. In all living… read more here.
Keywords: carbonic anhydrases; highlight inhibition; co2; hco3 ... See more keywords