Inhibition of Galectin-3 Impairs Antifungal Immune Response in Fungal Keratitis
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/8316004
Abstract: Galectin-3 is one of the galectin family members which are master regulators of immune homeostasis, especially in infectious diseases. However, its mechanism of immune regulation in fungal keratitis has not been thoroughly studied. Our study… read more here.
Keywords: keratitis; fungal keratitis; antifungal immune; inhibition galectin ... See more keywords
Functions and Inhibition of Galectin-7, an Emerging Target in Cellular Pathophysiology
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11111720
Abstract: Galectin-7 is a soluble unglycosylated lectin that is able to bind specifically to β-galactosides. It has been described to be involved in apoptosis, proliferation and differentiation, but also in cell adhesion and migration. Several disorders… read more here.
Keywords: galectin; target cellular; functions inhibition; emerging target ... See more keywords
Therapeutic inhibition of galectin‑3 improves cardiomyocyte apoptosis and survival during heart failure.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.8323
Abstract: Galectin-3 is an important mediator of cardiac fibrosis and heart failure. Cell viability of cardiomyocytes was measured using a CCK‑8 assay; flow cytometry was employed for the detection of the cell cycle and cardiomyocytes apoptosis.… read more here.
Keywords: cell; inhibition galectin; heart failure; galectin ... See more keywords