Loading docetaxel in β-cyclodextrin-based micelles for enhanced oral chemotherapy through inhibition of P-glycoprotein mediated efflux transport
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DOI: 10.1039/c7ra03180g
Abstract: Oral administration of BCS Class IV drugs still faces great challenges owing to their poor dissolubility in the gastro-intestinal (GI) tract and low permeation capacity across the GI membrane. Here, we constructed a β-cyclodextrin-based polymeric… read more here.
Keywords: glycoprotein mediated; dtx; inhibition glycoprotein; mediated efflux ... See more keywords