Inhibition of HIF-1α accumulation in prostate cancer cells is initiated during early stages of mammalian orthoreovirus infection.
Sign Up to like & getrecommendations! Published in 2021 at "Virology"
DOI: 10.1016/j.virol.2021.02.014
Abstract: Mammalian orthoreovirus (MRV) is a safe and effective cancer killing virus that has completed Phase I-III clinical trials against numerous cancer types. While many patients experience benefit from MRV therapy, pre-defined set points necessary for… read more here.
Keywords: mammalian orthoreovirus; inhibition hif; infection; inhibition ... See more keywords
Anticancer Activity of Natural Flavonoids: Inhibition of HIF-1α Signaling Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Current Organic Chemistry"
DOI: 10.2174/1385272823666191203122030
Abstract: Rapid tumor growth is dependent on the capability of tumor blood vessels and glycolysis to provide oxygen and nutrients. Tumor hypoxia is a common characteristic of many solid tumors, and it essentially happens when the… read more here.
Keywords: natural flavonoids; inhibition hif; anticancer activity; tumor ... See more keywords