Articles with "inhibition hybrid" as a keyword



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Towards Arginase Inhibition: Hybrid SAR Protocol for Property Mapping of Chlorinated N-arylcinnamamides

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043611

Abstract: A series of seventeen 4-chlorocinnamanilides and seventeen 3,4-dichlorocinnamanilides were characterized for their antiplasmodial activity. In vitro screening on a chloroquine-sensitive strain of Plasmodium falciparum 3D7/MRA-102 highlighted that 23 compounds possessed IC50 < 30 µM. Typically,… read more here.

Keywords: arginase; towards arginase; hybrid sar; inhibition hybrid ... See more keywords