Chloride channel inhibition improves neuromuscular function under conditions mimicking neuromuscular disorders
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DOI: 10.1111/apha.13690
Abstract: The skeletal muscle Cl− channels, the ClC‐1 channels, stabilize the resting membrane potential and dampen muscle fibre excitability. This study explored whether ClC‐1 inhibition can recover nerve‐stimulated force in isolated muscle under conditions of compromised… read more here.
Keywords: inhibition improves; inhibition; channel inhibition; chloride channel ... See more keywords
HDAC3 inhibition improves urinary‐concentrating defect in hypokalaemia by promoting AQP2 transcription
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DOI: 10.1111/apha.13802
Abstract: This study investigated whether enhanced histone acetylation, achieved by inhibiting histone deacetylases (HDACs), could prevent decreased aquaporin‐2 (AQP2) expression during hypokalaemia. read more here.
Keywords: inhibition improves; hdac3 inhibition; hypokalaemia; concentrating defect ... See more keywords