SGLT2 inhibition and kidney protection.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical science"
DOI: 10.1042/cs20171298
Abstract: Type 2 diabetes mellitus (T2DM) is a growing public health concern worldwide. Numerous drug classes are available for treatment, however, their efficacy with regard to diabetes-induced renal and cardiovascular (CV) complications remains limited. Inhibitors of… read more here.
Keywords: sglt2 inhibitors; inhibition kidney; inhibition; sglt2 inhibition ... See more keywords
mTOR Inhibition and Kidney Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/tp.0000000000001729
Abstract: Abstract Mammalian or mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that plays essential roles in cell growth, proliferation, metabolism, and survival. Increased activation of the mTOR pathway is observed in patients and animal… read more here.
Keywords: kidney diseases; mtor inhibition; inhibition kidney; mtor ... See more keywords