Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109571
Abstract: Soluble epoxide hydrolase (sEH) is a potential drug target to treat inflammation and neurodegenerative diseases. In this study, we found that the extract of Inula britanica exhibited significantly inhibitory effects against sEH, therefore, we investigated… read more here.
Keywords: soluble epoxide; epoxide hydrolase; inula britanica; inhibition kinetics ... See more keywords
Tyrosinase inhibition by a rare neolignan: Inhibition kinetics and mechanistic insights through in vitro and in silico studies
Sign Up to like & getrecommendations! Published in 2018 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2018.06.003
Abstract: Neolignans are a large group of polyphenols found in plants and exhibit a wide range of bioactivities including cytotoxicity, apoptosis inducer, antimalarial and antifungal effects, acetylcholinesterase, tyrosinase, and α-glucosidase inhibition. In this study we tested… read more here.
Keywords: tyrosinase inhibition; neolignan inhibition; inhibition; inhibition kinetics ... See more keywords
Computational prediction integrating the inhibition kinetics of gallotannin on α-glucosidase.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.106
Abstract: Due to the finding that inhibition of α-glucosidase is directly associated with treatment of several diseases, the development of a selective inhibitor for targeting α-glucosidase is important. Gallotannin (GT) is a natural ingredient that has… read more here.
Keywords: integrating inhibition; inhibition; inhibition kinetics; computational prediction ... See more keywords
Steady-state current in product inhibition kinetics in an amperometric biosensor: Adomian decomposition and Taylor series method
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DOI: 10.1016/j.jelechem.2021.115103
Abstract: Abstract Theoretical models of an amperometric biosensor with product inhibition kinetics are discussed. These models are based on non-stationary diffusion equations containing a non-linear term related to non-Michaelis-Menten kinetics of the enzymatic reaction. The approximate… read more here.
Keywords: inhibition kinetics; method; product inhibition; product ... See more keywords
Net growth rate of continuum heterogeneous biofilms with inhibition kinetics
Sign Up to like & getrecommendations! Published in 2017 at "NPJ Biofilms and Microbiomes"
DOI: 10.1038/s41522-017-0045-y
Abstract: Biofilm systems can be modeled using a variety of analytical and numerical approaches, usually by making simplifying assumptions regarding biofilm heterogeneity and activity as well as effective diffusivity. Inhibition kinetics, albeit common in experimental systems,… read more here.
Keywords: inhibition kinetics; biofilm; rate; growth ... See more keywords
Application of computational simulation integrating inhibition kinetics for detecting tyrosinase inhibitor: salsalate is a new inhibitor.
Sign Up to like & getrecommendations! Published in 2022 at "Protein and peptide letters"
DOI: 10.2174/0929866529666220805145244
Abstract: BACKGROUND Tyrosinase inhibitor developments have been widely attended by investigators for their various applications. OBJECTIVE A combination of virtual screening of docking simulations and biochemical inhibition kinetics was performed to find a new inhibitor of… read more here.
Keywords: inhibition kinetics; application; new inhibitor; inhibitor ... See more keywords