Pharmacological inhibition of Kv1.3 channel impairs TLR3/4 activation and type I IFN response and confers protection against Listeria monocytogenes infection.
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DOI: 10.1016/j.phrs.2022.106112
Abstract: Emerging data have demonstrated the critical roles of potassium efflux in the innate immune system. However, the role of potassium efflux in TLR3/4 activation and type I interferon (IFN) responses are not well elucidated. In… read more here.
Keywords: kv1 channel; ifn; activation; inhibition kv1 ... See more keywords