A new pimarane-type diterpene obtained by biotransformation inhibits human HCT-116 colorectal carcinoma through inhibition of LTA4H activity
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DOI: 10.1007/s00044-020-02520-9
Abstract: Chronic inflammation mediated by several markers promotes cancer progression. Leukotriene A4 hydrolase (LTA4H), an inflammatory marker, is highly expressed in colorectal cancer. Therefore, inhibition of LTA4H could reduce the incidence and progression of this cancer… read more here.
Keywords: hct 116; inhibition lta4h; activity; pimarane type ... See more keywords