Articles with "inhibition lysosomal" as a keyword



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Dual functions of iridium(III) 2-phenylpyridine complexes: Metastasis inhibition and lysosomal damage.

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Published in 2020 at "Journal of inorganic biochemistry"

DOI: 10.1016/j.jinorgbio.2019.110983

Abstract: Six N-phenylcarbazole/triphenylamine-appended half-sandwich iridium(III) 2-phenylpyridine complexes ([(η5-Cp*)Ir(C^N)Cl]) were prepared and characterized. Compared with cisplatin, these complexes exhibited potential antitumor activity against A549 and HeLa tumor cells, with IC50 values (half-maximum inhibitory concentration) that changed from… read more here.

Keywords: iii phenylpyridine; iridium iii; phenylpyridine complexes; dual functions ... See more keywords