Exploring inhibition mechanism and nature of lipase by Ligupurpuroside A extracted from Ku-Ding tea
Sign Up to like & getrecommendations! Published in 2018 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-018-2194-9
Abstract: Enzyme-activity essay demonstrated that Ligupurpuroside A acts as a natural inhibitor of lipase in a competitive manner. The inhibition mechanism and nature of lipase by Ligupurpuroside A were investigated by fluorescence spectra, UV–Vis absorption spectra,… read more here.
Keywords: fluorescence; lipase ligupurpuroside; lipase; inhibition mechanism ... See more keywords
Mechanistic insights into the inhibition mechanism of cysteine cathepsins by chalcone-based inhibitors—a QM cluster model approach
Sign Up to like & getrecommendations! Published in 2019 at "Structural Chemistry"
DOI: 10.1007/s11224-018-1273-3
Abstract: Cathepsins are the most abundant cysteine proteases involved in many physiological processes. The imbalance between the natural cysteine protease inhibitors and cathepsins leads to many pathological conditions such as cancer, osteoporosis, and osteoarthritis. Thus, cysteine… read more here.
Keywords: cysteine; chalcone based; cysteine cathepsins; inhibition mechanism ... See more keywords
Unveiling the inhibition mechanism of an effective inhibitor for AZ91 Mg alloy
Sign Up to like & getrecommendations! Published in 2019 at "Corrosion Science"
DOI: 10.1016/j.corsci.2018.12.025
Abstract: Abstract The inhibition mechanism of a high-efficiency corrosion inhibitor (sodium dodecyl sulfate, SDS) is unveiled and the strategy to design effective inhibitors for Mg alloys is suggested. It was found that SDS is chemically absorbed… read more here.
Keywords: unveiling inhibition; inhibitor; corrosion; inhibition mechanism ... See more keywords
The inhibition mechanism of the texture deterioration of tilapia fillets during partial freezing after treatment with polyphenols.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.127647
Abstract: The inhibition mechanism of the texture deterioration of tilapia fillets after treatment with polyphenols during partial freezing for 49 days was studied. Carnosic acid (CA), procyanidin (PA), quercetin (QE), and resveratrol (RSV) treatments had significantly higher… read more here.
Keywords: mechanism texture; tilapia fillets; partial freezing; texture ... See more keywords
Inhibition mechanism of baicalein and baicalin on xanthine oxidase and their synergistic effect with allopurinol
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2018.10.005
Abstract: Abstract Suppression of xanthine oxidase (XO) may contribute to control hyperuricemia and gout. In this study, baicalein and baicalin, two dietary flavones, were found to inhibit the formation of uric acid and generation of superoxide… read more here.
Keywords: xanthine oxidase; inhibition mechanism; baicalein baicalin;
Electrophysiological study of the violence inhibition mechanism in relation to callous-unemotional and aggressive traits.
Sign Up to like & getrecommendations! Published in 2017 at "Personality and Individual Differences"
DOI: 10.1016/j.paid.2017.01.049
Abstract: Abstract The violence inhibition mechanism (VIM) proposes that observing another’s distress inhibits responses that can lead to violent behaviour. Dysfunction of this system is associated with disorders characterised by aggressive and callous-unemotional traits, such as… read more here.
Keywords: aggressive traits; violence inhibition; inhibition mechanism; callous unemotional ... See more keywords
Study on the Chemical Inhibition Mechanism of DBHA on Free Radical Reaction during Spontaneous Combustion of Coal
Sign Up to like & getrecommendations! Published in 2020 at "Energy & Fuels"
DOI: 10.1021/acs.energyfuels.0c00226
Abstract: It is imperative to have an in-depth understanding of the chemical inhibition mechanism for spontaneous combustion of coal, not only for controlling and preventing spontaneous combustion of coal in... read more here.
Keywords: chemical inhibition; inhibition mechanism; spontaneous combustion; combustion coal ... See more keywords
Binding Modes of a Glycopeptidomimetic Molecule on Aβ Protofibrils: Implication for Its Inhibition Mechanism.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.8b00341
Abstract: We recently reported that a glycopeptidomimetic molecule significantly delays the fibrillization process of Aβ42 peptide involved in Alzheimer's disease. However, the binding mode of this compound, named 3β, was not determined at the atomic scale,… read more here.
Keywords: glycopeptidomimetic molecule; binding modes; inhibition mechanism; mechanism ... See more keywords
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-23313-7
Abstract: The SARS-CoV-2 pandemic has triggered global efforts to develop therapeutics. The main protease of SARS-CoV-2 (Mpro), critical for viral replication, is a key target for therapeutic development. An organoselenium drug called ebselen has been demonstrated… read more here.
Keywords: sars cov; main protease; inhibition mechanism;
Novel potent natural peroxidases inhibitors with in vitro assays, inhibition mechanism and molecular docking of phenolic compounds and alkaloids
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1808073
Abstract: Abstract Peroxidase inhibition produced by phenolic compounds as hispidin and gallic acid, alkaloids as harmine and natural extracts of Inonotus hispidus, and Marrubium vulgare were investigated in this study. No further studies have been found… read more here.
Keywords: inhibition; results show; phenolic compounds; inhibition mechanism ... See more keywords
The inhibition mechanism of epilepsy disease in a computational model
Sign Up to like & getrecommendations! Published in 2022 at "Technology and Health Care"
DOI: 10.3233/thc-228015
Abstract: BACKGROUND: The mechanism of prevention and treatment of epilepsy is a hot issue in theoretical research. OBJECTIVE: In this paper, we studied the control mechanism of the generalized spike-and-wave discharges (GSWD) by different types of… read more here.
Keywords: inhibition mechanism; computational model; model; mechanism ... See more keywords