Articles with "inhibition mir" as a keyword



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Inhibition of miR-219 Alleviates Arsenic-Induced Learning and Memory Impairments and Synaptic Damage Through Up-regulating CaMKII in the Hippocampus

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Published in 2018 at "Neurochemical Research"

DOI: 10.1007/s11064-018-2500-4

Abstract: Epidemiological investigations and experimental studies indicate that chronic arsenic exposure can reduce learning and memory function. However, the underlying mechanism of this effect remains largely unknown. Emerging evidence suggests that microRNA (miRNA) play an important… read more here.

Keywords: hippocampus; inhibition mir; learning memory; arsenic induced ... See more keywords
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Inhibition of miR-103-3p Preserves Neurovascular Integrity Through Caveolin-1 in Experimental Subarachnoid Hemorrhage

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Published in 2021 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2021.03.007

Abstract: Caveolin-1 (Cav-1) is a constitutive structural protein of caveolae in the plasma membrane. It plays an important role in maintaining blood brain barrier (BBB) integrity. In this study, we identified that miR-103-3p, a hypoxia-responsive miRNA,… read more here.

Keywords: mir 103; inhibition mir; subarachnoid hemorrhage; integrity ... See more keywords
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Inhibition of miR-1224 suppresses hypoxia/reoxygenation-induced oxidative stress and apoptosis in cardiomyocytes through targeting GPX4.

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Published in 2021 at "Experimental and molecular pathology"

DOI: 10.1016/j.yexmp.2021.104645

Abstract: We have focused on the underlying role of miR-1224 in cardiomyocyte injury stimulated by hypoxia/reoxygenation (H/R). In the current study, the rat cardiomyocyte cell line H9C2 was used to construct a H/R cell model to… read more here.

Keywords: apoptosis; mir; inhibition mir; mir 1224 ... See more keywords
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RETRACTED ARTICLE: Inhibition of miR-296-5p protects the heart from cardiac hypertrophy by targeting CACNG6

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Published in 2019 at "Gene Therapy"

DOI: 10.1038/s41434-019-0109-0

Abstract: Heart often undergoes mal-remodeling and hypertrophic growth in response to pathological stress. MiRNAs can regulate the cardiac function and participate in the regulation of cardiac hypertrophy. The present study aims at identifying the role of… read more here.

Keywords: mir 296; cardiac hypertrophy; inhibition mir; heart ... See more keywords
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Inhibition of miR-221-3p promotes axonal regeneration and repair of primary sensory neurons via regulating p27 expression

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Published in 2023 at "NeuroReport"

DOI: 10.1097/wnr.0000000000001912

Abstract: This study aimed to explore the key microRNA (miRNA) playing a vital role in axonal regeneration with a hostile microenvironment after spinal cord injury. Based on the theory that sciatic nerve conditioning injury (SNCI) could… read more here.

Keywords: regeneration; p27; axonal regeneration; inhibition mir ... See more keywords
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Inhibition of miR-153 ameliorates ischemia/reperfusion-induced cardiomyocytes apoptosis by regulating Nrf2/HO-1 signaling in rats

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Published in 2020 at "BioMedical Engineering OnLine"

DOI: 10.1186/s12938-020-0759-6

Abstract: Background Previous in vitro studies demonstrated that suppression of microRNAs might protect cardiomyocytes and neurons against oxygen–glucose deprivation and reoxygenation (OGD/R)-induced cell apoptosis. However, whether the protective effect of miR-153-inhibition on cardiomyocytes can be observed… read more here.

Keywords: cardiomyocytes apoptosis; inhibition mir; mir 153; induced cardiomyocytes ... See more keywords
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Inhibition of miR-221 influences bladder cancer cell proliferation and apoptosis.

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Published in 2020 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202007_22193

Abstract: Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "Inhibition of miR-221 influences bladder cancer cell proliferation and… read more here.

Keywords: mir 221; cancer cell; bladder cancer; inhibition mir ... See more keywords
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Inhibition of miR-128 Enhances Vocal Sequence Organization in Juvenile Songbirds

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Published in 2022 at "Frontiers in Behavioral Neuroscience"

DOI: 10.3389/fnbeh.2022.833383

Abstract: The molecular mechanisms underlying learned vocal communication are not well characterized. This is a major barrier for developing treatments for conditions affecting social communication, such as autism spectrum disorder (ASD). Our group previously generated an… read more here.

Keywords: vocal sequence; stereotypy; learned vocal; inhibition mir ... See more keywords