Identification of Structural Features for the Inhibition of OAT3-Mediated Uptake of Enalaprilat by Selected Drugs and Flavonoids
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DOI: 10.3389/fphar.2020.00802
Abstract: Enalaprilat is the active metabolite of enalapril, a widely used antihypertension drug. The human organic anion transporter 3 (OAT3), which is highly expressed in the kidney, plays a critical role in the renal clearance of… read more here.
Keywords: uptake enalaprilat; mediated uptake; inhibition oat3; drug ... See more keywords