Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers
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DOI: 10.1007/s13238-019-0634-z
Abstract: While the majority of all human cancers counteract telomere shortening by expressing telomerase, ~15% of all cancers maintain telomere length by a telomerase-independent mechanism known as alternative lengthening of telomeres (ALT). Here, we show that high… read more here.
Keywords: apoptosis; inhibition p53; p53 akt; p53 ... See more keywords