Sustained inhibition of PARP-1 activity delays glioblastoma recurrence by enhancing radiation-induced senescence.
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DOI: 10.1016/j.canlet.2020.06.023
Abstract: Glioblastoma (GBM) is the most common primary brain tumor and is highly aggressive with a median survival of 15 months. We have previously shown that residual cells of GBM form multinucleated giant cells (MNGCs) showing… read more here.
Keywords: parp activity; recurrence; parp; inhibition parp ... See more keywords