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GPR146 inhibition protects against atherosclerosis

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Published in 2019 at "Nature Reviews Drug Discovery"

DOI: 10.1038/d41573-019-00204-7

Abstract: Human genetic studies have established the orphan G proteincoupled receptor gene, GPR146, as a regulator of plasma cholesterol levels. In line with these findings, Yu et al. report that depletion of GPR146 in mice substantially… read more here.

Keywords: inhibition protects; gpr146 inhibition; atherosclerosis; protects atherosclerosis ... See more keywords