Selective Inhibition of PTP1B by New Anthraquinone Glycosides from Knoxia valerianoides.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00879
Abstract: Protein tyrosine phosphatase 1B (PTP1B) is highly validated as a therapeutic target for type 2 diabetes. However, active site-directed PTP1B inhibitors generally suffer from poor selectivity and bioavailability. Inspired by the identification of a unique… read more here.
Keywords: selective inhibition; knoxia valerianoides; inhibition ptp1b; anthraquinone glycosides ... See more keywords