Inhibition of S100B prevents ex vivo demyelination and improves EAE clinical score
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DOI: 10.1016/j.freeradbiomed.2018.04.504
Abstract: The autoimmune disease multiple sclerosis (MS), with strong inflammation and neurodegeneration, affects motor and cognitive functions. S100B is increased in CSF, serum and post-mortem plaques of MS patients being correlated with demyelination and glial reactivity.… read more here.
Keywords: demyelination; inhibition s100b; clinical score;