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   Articles with "inhibition therapy" as a keyword



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Thrown for a Loop: Awakening BORIS to Evade ALK Inhibition Therapy.

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recommendations! Published in 2019 at "Cancer cell"

DOI: 10.1016/j.ccell.2019.09.009

Abstract: Mechanisms of acquired resistance to ALK inhibition therapy in neuroblastoma have not yet been elucidated. In a recent issue of Nature, Debruyne et al. demonstrate that resistant MYCN-amplified ALK-mutated neuroblastoma cells overexpress BORIS, resulting in wide-ranging… read more here.

Keywords: alk inhibition; thrown loop; inhibition therapy; alk ... See more keywords

Cortical Reorganization Following Psychoeducational Counselling and Residual Inhibition Therapy (RIT) in Individuals with Tinnitus

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recommendations! Published in 2022 at "International Archives of Otorhinolaryngology"

DOI: 10.1055/s-0042-1743287

Abstract: Introduction  Psychoeducational counselling and residual inhibition therapy (RIT) are traditional approaches used in many clinics to manage tinnitus. However, neurophysiological studies to evaluate posttreatment perceptual and functional cortical changes in humans are scarce. Objectives  The… read more here.

Keywords: therapy rit; counselling residual; residual inhibition; inhibition therapy ... See more keywords
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Pathophysiology of large vessel vasculitis and utility of interleukin-6 inhibition therapy

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recommendations! Published in 2019 at "Modern Rheumatology"

DOI: 10.1080/14397595.2018.1546358

Abstract: Abstract Takayasu arteritis (TAK) and giant cell arteritis (GCA) affect mainly large- and medium-sized arteries. In refractory cases, vascular remodeling progresses and leads to serious outcomes. Studies have demonstrated that cytokines such as interleukin (IL)-6… read more here.

Keywords: inhibition therapy; pathophysiology large; vessel vasculitis; therapy ... See more keywords

Synergistic Immunoregulation: harnessing CircRNAs and PiRNAs to Amplify PD-1/PD-L1 Inhibition Therapy

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recommendations! Published in 2024 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s461289

Abstract: Abstract The utilization of PD-1/PD-L1 inhibitors marks a significant advancement in cancer therapy. However, the efficacy of monotherapy is still disappointing in a substantial subset of patients, necessitating the exploration of combinational strategies. Emerging from… read more here.

Keywords: cancer; inhibition therapy; synergistic immunoregulation; therapy ... See more keywords
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Cardiac Complications in Immune Checkpoint Inhibition Therapy

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recommendations! Published in 2019 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2019.00003

Abstract: Immune checkpoint inhibitors (ICIs) have changed the treatment landscape of advanced cancers. Unfortunately, these agents can induce a wide spectrum of immune-related adverse events (irAEs) through activation of immune responses in non-target organs, including the… read more here.

Keywords: immune checkpoint; inhibition therapy; checkpoint inhibition; complications immune ... See more keywords