Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
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DOI: 10.1124/dmd.121.000668
Abstract: Lurbinectedin is a novel and potent selective inhibitor of active transcription of protein-coding genes, triggering apoptosis of cancerous cells. It has been approved for the treatment of patients with metastatic small-cell lung cancer with disease… read more here.
Keywords: inhibitor active; transcription protein; active transcription; selective inhibitor ... See more keywords