Jak2 Inhibitor AG490 Improved Poststroke Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat Model of Ischemic Stroke
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DOI: 10.3390/antiox10121958
Abstract: Poststroke hyperglycemia and inflammation have been implicated in the pathogenesis of stroke. Janus Kinase 2 (Jak2), a catalytic signaling component for cytokine receptors such as Interleukin-6 (IL-6), has inflammatory and metabolic properties. This study aimed… read more here.
Keywords: jak2 inhibitor; inhibitor ag490; inflammation metabolic; rat model ... See more keywords