IL-4Rα Inhibitor for Atopic Disease
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DOI: 10.1016/j.cell.2017.06.046
Abstract: Dupilumab is a fully human IgG4 monoclonal antibody directed against the IL-4Rα subunit of IL-4 and IL-13 receptors. It blocks the signaling pathways of IL-4 and IL-13, key cytokines that drive type 2 inflammatory response.… read more here.
Keywords: atopic disease; atopic; inhibitor atopic;