Macrocyclization of a potent PACE4 inhibitor: Benefits and limitations.
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DOI: 10.1016/j.ejcb.2017.04.001
Abstract: PACE4, one of the seven members of the proprotein convertase family, plays an important role in the progression of prostate cancer. Therefore, its inhibition has become an attractive target to develop new therapies against this… read more here.
Keywords: inhibitor; pace4; macrocyclization potent; inhibitor benefits ... See more keywords