Long-Range Changes in Neurolysin Dynamics Upon Inhibitor Binding.
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DOI: 10.1021/acs.jctc.7b00944
Abstract: Crystal structures of neurolysin, a zinc metallopeptidase, do not show a significant conformational change upon the binding of an allosteric inhibitor. Neurolysin has a deep channel where it hydrolyzes a short neuropeptide neurotensin to create… read more here.
Keywords: inhibitor bound; inhibitor binding; inhibitor; long range ... See more keywords