Sodium-glucose cotransporter 2 inhibitor canagliflozin attenuates lung cancer cell proliferation in vitro
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DOI: 10.1007/s13340-021-00494-6
Abstract: Cancer is a major cause of death in patients with type 2 diabetes mellitus (T2DM) and lung cancer is one of the most prevalent cancers in patients with T2DM. In the present study, we examined… read more here.
Keywords: cancer; cell; inhibitor canagliflozin; lung cancer ... See more keywords
The SGLT2 Inhibitor Canagliflozin Induces Catabolic Transcriptional and Metabolic Switching and Increases FGF-21 in Mice with Dietary Obesity
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DOI: 10.2337/db18-1836-p
Abstract: Given the impact of SGLT2 inhibitors to reduce overall mortality and CV risk in T2D, improved understanding of cellular and transcriptional mechanisms responsible for metabolic effects is required. We fed C57BL/6J mice a 60% high… read more here.
Keywords: research support; sglt2 inhibitor; support self; inhibitor canagliflozin ... See more keywords