Articles with "inhibitor cb988" as a keyword



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Abstract 3232: Development of novel Btk inhibitor, CB988 targering ibrutinib-resistant Btk C481S mutant

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-3232

Abstract: Introduction: Bruton9s tyrosine kinase (Btk) is a member of the Tec family of cytoplasmic tyrosine kinase. Btk plays a crucial role in the BCR signaling, essential for B-cell development, and Btk has been recognized as… read more here.

Keywords: inhibitor cb988; btk c481s; btk; btk inhibitor ... See more keywords