Articles with "inhibitor class" as a keyword



A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis

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Published in 2024 at "British Journal of Pharmacology"

DOI: 10.1111/bph.17306

Abstract: Most inhibitors of histone deacetylases (HDACs) are not selective and are cytotoxic. Some have anti‐inflammatory activity in disease models, but cytotoxicity prevents long‐term uses in non‐fatal diseases. Inhibitors selective for class IIa HDACs are much… read more here.

Keywords: novel inhibitor; class iia; inhibitor class; histone deacetylases ... See more keywords