Physosmotic Induction of Chondrogenic Maturation Is TGF-β Dependent and Enhanced by Calcineurin Inhibitor FK506
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DOI: 10.3390/ijms23095110
Abstract: Increasing extracellular osmolarity 100 mOsm/kg above plasma level to the physiological levels for cartilage induces chondrogenic marker expression and the differentiation of chondroprogenitor cells. The calcineurin inhibitor FK506 has been reported to modulate the hypertrophic… read more here.
Keywords: cell; inhibitor fk506; calcineurin inhibitor; osmolarity ... See more keywords